I have a web based application running on port :1095. Its NOT on the WEB server and uses its own webservice. This local computer is dedicated for timesheet application only. I can reach to this computer by specifying port number in the url. Like http://abc.def.com:1095/ but I need to get rid of the number at the end. We dont have DNS server, can I setup a subdomain for this computer???

Well, you could always set up a portmap on your firewall/router to point to that computer's internal IP address. This raises all kinds of security issues though and you would want to consult someone before doing so.

The portmapping is probably the best option, but you could also setup an http redirect like this on the port 80 (HTTP) site with something like this:

<meta http-equiv="refresh" content="0;url=http://abc.def.com:1095">